Ipamorelin CAS: 170851-70-4 IPAMORELIN;AIB-HIS-D-NAL(2)-D-PHE-LYS-NH2
Hoʻohana
ʻO Ipamorelin (INN) (code development NNC 26-0161) he peptide-selective agonist o auxin hoʻokuʻu i nā peptides / somatosecretin receptors (GHS) a me ka somatosecretin.He pentapeptide ia me ke kaʻina amino acid Aib-His-D-2-Nal - D-Phe -Lys-NH 2, i loaʻa mai GHRP-1.
Hoʻonui nui ʻo Ipamorelin i ka nui o ka hormone ulu plasma (GH) i nā holoholona a me nā kānaka.Eia kekahi, ua hoʻoulu ʻia ka ipamorelin i ke kaumaha o nā holoholona.E like me pralmorelin a me GHRP-6, ʻaʻole pili ka ipamorelin i ka prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), a i ʻole thyrotropin (TSH).Eia naʻe, ʻaʻole like me pramoline (GHRP-2) a me GHRP-6, akā like me ka hormone hoʻokuʻu ʻana i ka hormone ulu (GHRH), ʻaʻole hoʻoulu ʻia ka iparerelin i ka huna ʻana o ka hormone adrenocorticotropic (ACTH) a i ʻole cortisol a koho nui loa no ka hoʻoulu ʻana i ka huna GH wale nō.
Ua hoʻokumu mua ʻia ʻo Ipamorelin e Novo Nordisk a ua alakaʻi i nā hoʻokolohua lapaʻau ʻo Phase II iā ia iho ma ke ʻano he lapaʻau no ka ilobstruction postoperative, akā ua hoʻopau ʻia ma muli o ka nele o ka pono.
Ua hoʻohana ʻia ʻo Ipamorelin e nā mea pāʻani ma ke ʻano he lāʻau hoʻoikaika hana.
